Characterization of ribonuclease P RNAs from thermophilic bacteria
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چکیده
منابع مشابه
Characterization of ribonuclease P RNAs from thermophilic bacteria.
The catalytic RNA component of bacterial RNase P is responsible for the removal of 5' leader sequences from precursor tRNAs. As part of an on-going phylogenetic comparative characterization of bacterial RNase P, the genes encoding RNase P RNA from the thermophiles Thermotoga maritima, Thermotoga neapolitana, Thermus aquaticus, and a mesophilic relative of the latter, Deinococcus radiodurans, ha...
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Ribonuclease P (RNase P) is the site-specific endoribonuclease that cleaves leader sequences from pre-tRNAs (see 1, 2 for reviews). Cleavage by RNase P absolutely requires divalent cation, preferably Mg+ + (3), and produces 3'-hydroxyl and 5'-phosphate ends (4). Although RNase P is thought to be present in all living cells, the enzyme is best understood in the bacteria Escherichia coli and Baci...
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The secondary structure of bacterial RNase P RNA, a ribozyme responsible for the maturation of the 5' end of tRNAs, is well established on the basis of sequence comparison analysis. RNase P RNA secondary structures fall into two types, A and B, which share a common core formed by the assembly of two main folding domains, but differ in their peripheral elements.A revised alignment of 137 availab...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1993
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/21.3.671